The cees dekker Diaries
The cees dekker Diaries
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Multicolor imaging from the bacterial nucleoid and mobile division proteins with blue, orange, and near-infrared fluorescent proteins
I am able to barely think about how I, being a geneticist, would be capable to find out basic physics, let alone contend at the best. How did you go about this?
We build stage-of-treatment diagnostics take a look at of neglected tropical conditions inside resource-confined options, according to Crspr/Cas9 detecting of pathogen’s DNA in body fluids.
Microbiology has only been around to get a century, given that we started to examine micro-organisms far more severely. I assumed nanobiology was an correct time period, simply because all molecular biological related interactions take place in the nanoscale: a protein is several nanometres in measurement, DNA is 2 nm thick.’
We shape bacteria into sorts that deviate from their pure phenotype. Specially, I will present our ability to condition Stay E. coli microorganisms into novel shapes such as rectangles, squares, triangles and circles.
Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in pink, and also a 3D rendering with the movement with the DNA rod is displayed.
‘You shouldn't just think of the queries of tomorrow, but additionally consider the issues on the day right after tomorrow’
There was a single difficulty however — we did not observe any measurable electrical conduction from The one polymer molecules. We concluded that at The one-molecule degree, conducting polymers had been really not such terrific conductors, which was alternatively disappointing. We Consequently broadened our look at to try to find extra promising molecules.
[fourteen] In 2005 Dekker became associated with Netherlands-extensive conversations about Clever Style, a movement that he has due to the fact Evidently distanced himself from. Dekker advocates that science and faith aren't in opposition but might be harmonized.
Afterwards we spoke all over again briefly because Dekker felt that our dialogue of his religion speedily became purely philosophical, whereas In addition it concretely allows him in his get the job done.
2005, discovery of your system of DNA uncoiling by topoisomerase enzymes; discovery of extensive-vary conformational variations in Mre11/DNA maintenance complexes; and to start with drive measurements with a https://www.ceesdekker.net DNA molecule in a very nanopore
Example (2) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is proven in grey, the rim in the pore is highlighted in purple, and also a 3D rendering of your movement of the DNA rod is displayed.